Loyola University Chicago

Department of Chemistry and Biochemistry

2017 Denkewalter Lecture

The 2017 Denkewalter Lecturer will be Dr. Elizabeth Nolan from the Department of Chemistry at the Massachusetts Institute of Technology (MIT). Dr. Nolan was the recipient of the prestigious Eli Lilly Award in Biological Chemistry, for 201‌6. ‌

Topic: "Chemical Explorations of Human Innate Immunity and Microbial Pathogenesis"
Metal homeostasis plays a central role in the host/microbe interaction because transition metals are essential nutrients for all organisms. Invading microbial pathogens must acquire metal ions from the mammalian host to replicate and cause infection. The host innate immune system launches a metal-withholding response to deprive the microbes of these essential nutrients and thereby inhibit colonization. colonization. Studying the interplay between host and microbe for essential metal nutrients affords paradigms for discovering and elucidating new bioinorganic chemistry, advancing fundamental understanding of innate immunity and microbial pathogenesis, and creating new approaches to treat infectious disease. Vignettes from chemical and biological explorations of metal homeostasis at the host/microbe interface will be presented, including bioinorganic studies of the metal-sequestering human S100 proteins calprotectin (S100A8/S100A9 oligomer), S100A7 and S100A12.
Date: November 9, 2017
Time: 5:30 -6:30pm
Location: Flanner Hall Auditorium (FH 133)

The Reception & Poster Session

A poster presentation and reception is to take place prior to the Denkewalter Lecture, in the foyer outside Flanner Auditorium at 4:30pm. During the event, Loyola Graduate and Undergraduate students will have an opportunity to share information regarding the Chemistry research they have conducted in their respective labs groups.


Graduate student, Gregory Deye, presenting his research on surface reactivity of organic substrates to peer and fellow doctoral candidate, Susan Phan. (2016)