Loyola University Chicago

John Felice Rome Center

BIOL 282 Genetics

Spring 2016

 

Instructor:                       Dr. Paola Galluzzo

Loyola University Chicago John Felice Rome Center Email: pgalluzzo1@luc.edu

 

Lectures:                          Tuesday 7:00 pm –9:30 am

Office Hours:                  Tuesday 6:00-7:00 pm by Appointment Rm 104

 

Prerequisites:                 BIOL 102, and CHEM 102 or 106

 

Required Text:               “Concepts of Genetics” (11th Edition)

W.S. Klug, M.R. Cummings, C.A. Spencer and M.A. Palladino

Pearson/Benjamin Cummings Publishers, 2015.

Concepts of Genetics” (11th Edition) Student Handbook and Solutions Manual

H. Nickla Pearson Publishers, 2015.

 

Course Objective:          The goal of this course is to offer solid foundation in genetic fundamentals through an examination of the basic principles of genetics in eukaryotes and prokaryotes at the level of molecules, cells, and multicellular organisms, including humans.

Upon completion of this course the students will know and understand the basics of the molecular processes of DNA replication, transcription and translation as well as the important characteristics of the genetic code; the Mendelian modes of inheritance that govern passage of genetic traits across generation; the basic structure and function of DNA and chromosomes as well as how chromosomes move through mitosis and meiosis; the equilibrium equation and requirements for maintaining Hardy-Weinberg equilibrium in a population. The students will be able to solve problems and quizzes related to these topics.

 

Lecture and Homework Information:

  • Lectures start promptly. If you arrive late or must leave early for an urgent reason, please do so without disturbing your fellow students.
  • Please turn off or silence all mobile devices before lecture begins.
  • Slides for each lecture will be available on Sakai
  • Problem sets are assigned on a regular basis throughout the semester

 

 

Studying for class:         Bio 282 covers a significant amount of material. The book is very detailed, but you are required to know the material discussed during lecture. Reading the book after lecture will allow you to better find and focus on the material covered in class. Study group are good to prepare for the exam where you can share your knowledge and solve your doubts. Please, feel free to ask questions during lecture and during office hour by appointment. Attendance is strongly advised as the exam will focus on my lectures and corresponding slides and I will draw exam questions from them.

 

 

Students with Special Needs: If you have any special needs in order to successfully complete this course, please inform me immediately so that available accommodations can be discussed and put into place.

 

 

Academic Integrity:      Cheating and plagiarism are severe academic offenses that are not tolerated at Loyola University. Any academic offense will result in a minimum penalty of an “F” grade for the assignment or the examination, failure of the exam, and possibly failure of the course. The incident will be reported to the student’s academic dean’s office to block the student from withdrawing from the course so that an F, rather than a W, will be recorded on the student’s transcript.

 

 

Exams and Grading:      There will be three non-cumulative exams, three during classes and the fourth during final exam week. The exams will consist of multiple choice-type questions and problems.

My expectations are that the following grade cutoff will apply

 

 

 

Grade

Cut off

 

 

A

88-100%

4.00

Excellent

A-

84-87%

3.67

 

B+

80-83%

3.33

 

B

76-79%

3.00

Good

B-

72-75%

2.67

 

C+

68-71%

2.33

 

C

64-67%

2.00

 

C-

60-63%

1.67

 

No passing grade

D+

56-59%

1.33

 

D

50-55%

1.00

Poor

F

0-49%

0.00

Failure

 

 

Missed Exams Policy:   There will be no makeup exams. A missed exam will be counted as your lowest score and your other in-class exams will be counted.

 

Tentative Lecture & Exam Schedule for spring semester 2016

Note: The following schedule is subject to change depending on pace of material coverage.

 

Date

 

 

Lecture

 

Lecture

Book

Chapter*

January

T

19

Welcome and Introduction to Genetics; Mendelian genetics

1

1,3

 

T

26

Pedigree; Sex linked inheritance; Linkage

2

4,7

February

T

2

Mapping in Eukaryotes: Somatic cell genetics; Chromosomal abnormalities

3

5,8

 

T

9

 

Exam 1 (Lecture 1-3 )

 

 

 

T

16

DNA structure; DNA Replication; Recombination

4

10,11

 

T

23

Bacterial genetics; Chromatin and Genome structure

5

6,12

March

T

1

Recombinant technology DNA

 

6

20

 

T

8

 

No classes-Spring Break

 

 

 

T

15

 

Exam 2 (Lectures 4-6)

 

 

 

T

22

Transcription; RNA processing; Translation; Genetic code

7

13

 

T

29

Translation; Genetic code; Mutation

8

14

April

T

5

Control of prokaryotic gene expression

9

16

 

T

12

 

Exam 3 (Lectures 7-9 )

 

 

 

T

19

Developmental genetic; The human genome; Using the human genome

10

18,21,22

 

T

26

Population genetics; Transposable elements

11

25,15

 

T

28

 

Final Exam 4 (Lecture )

 

 

* Book chapters refer to W.S Klug et al Concepts of Genetics” (11th Edition)