Simon Kaja

Associate Professor

Publications/Research Listings

Hariani, HN; Ghosh, AK; Rosen, SM; Tso, HY; Kessinger, C; Zhang, C; Jones, WK; Sappington, RM; Mitchell, CH; Stubbs, EB; Rao, VR; Kaja, S Lysyl oxidase like-1 deficiency in optic nerve head astrocytes elicits reactive astrocytosis and alters functional effects of astrocyte derived exosomes. Experimental eye research ; 240

Lelyte, I; Rao, VR; Kalesnykas, G; Ragauskas, S; Kaja, S; Ahmed, Z Prospects and limitations of cumate-inducible lentivirus as a tool for investigating VEGF-A-mediated pathology in diabetic retinopathy. Scientific reports ; 14 1

Kleinman, D; Iqbal, S; Ghosh, AK; Ogle, SD; Kaja, S; Mitchnick, M; Hakkarainen, JJ PLL-g-PEG Polymer Inhibits Antibody-Drug Conjugate Uptake into Human Corneal Epithelial Cells . Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics ;

Kaja, S; Iqbal, S; Pons Lopez, B; Molina Zaragoza, S; Mun, C; Flavin, MT; Jain, S Safety and tolerability of pooled human immune globulins after topical ophthalmic administration in New Zealand White rabbits. Cutaneous and ocular toxicology ;

Bacellar-Galdino, M., Kaja, S. Ocular Pharmacokinetic and Safety Studies ;

Manikandan, SK; Logan, A; Cerrada-Gimenez, M; Fitzhenry, L; Coffey, L; Kaja, S; Rani, S Immune System, Inflammation and Autoantigens in Wet Age-Related Macular Degeneration: Pathological Significance and Therapeutic Importance. Life (Basel, Switzerland) ; 13 12

Ghosh, AK; Cesna, R; Neverauskas, D; Žiniauskaite, A; Iqbal, S; Eby, JM; Ragauskas, S; Kaja, S Dietary Alcohol Consumption Elicits Corneal Toxicity Through the Generation of Cellular Oxidative Stress. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics ; 39 5

Lelyte, I; Ahmed, Z; Kaja, S; Kalesnykas, G Structure-Function Relationships in the Rodent Streptozotocin-Induced Model for Diabetic Retinopathy: A Systematic Review. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics ;

Ghosh, AK; Bacellar-Galdino, M; Iqbal, S; Pappenhagen, NE; Kaja, S Topical Porphyrin Antioxidant Protects Against Ocular Surface Pathology in a Novel Rabbit Model for Particulate Matter-Induced Dry Eye Disease. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics ;

Losenkova, K; Takeda, A; Ragauskas, S; Cerrada-Gimenez, M; Vähätupa, M; Kaja, S; Paul, ML; Schmies, CC; Rolshoven, G; Müller, CE; Sandholm, J; Jalkanen, S; Kalesnykas, G; Yegutkin, GG CD73 controls ocular adenosine levels and protects retina from light-induced phototoxicity. Cellular and molecular life sciences : CMLS ; 79 3

Acevedo-Jake, A; Shi, S; Siddiqui, Z; Sanyal, S; Schur, R; Kaja, S; Yuan, A; Kumar, VA Preclinical Efficacy of Pro- and Anti-Angiogenic Peptide Hydrogels to Treat Age-Related Macular Degeneration. Bioengineering (Basel, Switzerland) ; 8 12

Ghosh, AK; Thapa, R; Hariani, HN; Volyanyuk, M; Ogle, SD; Orloff, KA; Ankireddy, S; Lai, K; Žiniauskaite, A; Stubbs, EB; Kalesnykas, G; Hakkarainen, JJ; Langert, KA; Kaja, S Poly(lactic-co-glycolic acid) Nanoparticles Encapsulating the Prenylated Flavonoid, Xanthohumol, Protect Corneal Epithelial Cells from Dry Eye Disease-Associated Oxidative Stress. Pharmaceutics ; 13 9

Ghosh, AK; Rao, VR; Wisniewski, VJ; Zigrossi, AD; Floss, J; Koulen, P; Stubbs, EB; Kaja, S Differential Activation of Glioprotective Intracellular Signaling Pathways in Primary Optic Nerve Head Astrocytes after Treatment with Different Classes of Antioxidants. Antioxidants (Basel, Switzerland) ; 9 4

Pulido, I; Ollosi, S; Aparisi, S; Becker, JH; Aliena-Valero, A; Benet, M; Rodríguez, ML; López, A; Tamayo-Torres, E; Chuliá-Peris, L; García-Cañaveras, JC; Soucheray, M; Dalheim, AV; Salom, JB; Qiu, W; Kaja, S; Alcácer Fernández-Coronado, J; Alandes, S; Alcácer, J; Al-Shahrour, F; Borgia, JA; Juan, O; Nishimura, MI; Lahoz, A; Carretero, J; Shimamura, T Endothelin-1-mediated Drug Resistance in EGFR-mutant NSCLC. Cancer research ;

Breuer, EK; Fukushiro-Lopes, D; Dalheim, A; Burnette, M; Zartman, J; Kaja, S; Wells, C; Campo, L; Curtis, KJ; Romero-Moreno, R; Littlepage, LE; Niebur, GL; Hoskins, K; Nishimura, MI; Gentile, S Potassium channel activity controls breast cancer metastasis by affecting ß-catenin signaling. Cell death & disease ; 10 3

Žiniauskaite, A; Ragauskas, S; Ghosh, AK; Thapa, R; Roessler, AE; Koulen, P; Kalesnykas, G; Hakkarainen, JJ; Kaja, S Manganese(III) tetrakis(1-methyl-4-pyridyl) porphyrin, a superoxide dismutase mimetic, reduces disease severity in in vitro and in vivo models for dry-eye disease. The Ocular Surface ; 17 2

Kouzoukas, DE; Schreiber, JA; Tajuddin, NF; Kaja, S; Neafsey, EJ; Kim, HY; Collins, MA PARP inhibition in vivo blocks alcohol-induced brain neurodegeneration and neuroinflammatory cytosolic phospholipase A2 elevations. Neurochemistry international ; 129

Rao, VR; Lautz, JD; Kaja, S; Foecking, EM; Lukács, E; Stubbs, EB Mitochondrial-Targeted Antioxidants Attenuate TGF-ß2 Signaling in Human Trabecular Meshwork Cells. Investigative Ophthalmology & Visual Science ; 60 10

Rosen, SM; Kaja, S; De Alba, F Association of Transient Colorblindness With Sildenafil and Tadalafil. JAMA ophthalmology ;

Žiniauskaite, A; Ragauskas, S; Hakkarainen, JJ; Rich, CC; Baumgartner, R; Kalesnykas, G; Albers, DS; Kaja, S Efficacy of Trabodenoson in a Mouse Keratoconjunctivitis Sicca (KCS) Model for Dry-Eye Syndrome. Investigative Ophthalmology & Visual Science ; 59 7

Huang, J; Romero-Suarez, S; Lara, N; Mo, C; Kaja, S; Brotto, L; Dallas, SL; Johnson, ML; Jähn, K; Bonewald, LF; Brotto, M Crosstalk between MLO-Y4 osteocytes and C2C12 muscle cells is mediated by the Wnt/ß-catenin pathway. JBMR plus ; 1 2