Skip to main content
Back to LUC.edu
Microbiology and Immunology
Stritch School of Medicine
Request Info Visit Apply

Steve Baker, PhD

Assistant Professor

Microbiology & Immunology

Research Interests:

  • Contribution of host alternative RNA splicing the control of viral infection and immune regulation

Education

PhD:   University of Rochester School of Medicine & Dentistry
BS:     University at Buffalo (State University of New York)

 

Research Interests

Contribution of host alternative RNA splicing the control of viral infection and immune regulation

Publications/Research Listings

Aniseia Y, Waltari E, Frank M, Lima L, Rahman G, Zhou A, Kim Y-J, Huang H, Baker SF, Senbabaoglu Y, Peng D, Balla K. (2026). RNAquarium: an archive-scale atlas of zebrafish gene expression coupled with pan-taxonomic profiling reveals diverse viral drivers of transcriptomic state. bioRxiv. doi: 0.64898/2026.06.17.732950.

P Nath H, Guo Y, Baker SF. (2026). A novel ISG15 transcript restricts influenza A virus infection. bioRxiv. doi: 10.64898/2026.01.15.699784.

Jiang L, Hurwitz I, Wylezinski LS, Racke MK, Yan F, Ye F, Sheng Q, Leng S, Chung C, Stein CM, Li C-I, Kumar N, Ceccarelli M, Baker SF, Perkins DJ, Spurlock CF, Han L, Guo Y. (2026). ImmuSeeker: deep mining of immune-related gene family signatures through lineage reconstruction. Genome Biol. PMID: 41888873

Nath H, Arndt A, Mann JM, Baker SF. (2025). Tandem split-GFP influenza A viruses for sensitive and accurate replication analyses. Microbiol Spectr. PMID: 41247244

Jiang L, Baker SF, Ceccarelil M, Guo Y. (2025). Comprehensive Profiling of Computational Techniques for Sequencing-Based HLA Immune Signatures Extraction. HLA. PMID: 39957309

 

Mann JT, Riley BA, Baker SF. (2023). All differential on the splicing front: Host alternative splicing alters the landscape of virus-host conflict. Semin. Cell Dev. Biol. PMID: 36737258

P Mrass P, Kinjyo I, Byrum JR, Torres D, Baker SF, Cannon JL. (2022). CXCR4 controls movement and degranulation of CD8+ T cells in the influenza-infected lung via differential effects on interaction and tissue scanning. bioRxiv. Doi: 10.1101/2022.09.13.507813.

Baker SF, Meistermann H, Tzouros M, Baker A, Golling S, Siebourg Polster J, Ledwith MP, Gitter A, Augustin A, Javanbakht H, Mehle A. (2022). Alternative splicing liberates a cryptic cytoplasmic isoform of mitochondrial MECR that antagonizes influenza virus. PLoS Biol. PMID: 36542656. c, co-corresponding.

Baker SF, Ledwith MP, Mehle A. (2018). Differential Splicing of ANP32A in Birds Alters Its Ability to Stimulate RNA Synthesis by Restricted Influenza Polymerase. Cell Rep. PMID: 30184493

Baker SF, Nogales A, Finch C, Tuffy K, Domm W, Perez DR, Topham DJ, Martínez-Sobrido L. (2014). Influenza A and B intertypic reassortment through compatible viral packaging signals. J. Virol. PMID: 25008914

Nogales A, Baker SF, Ortiz-Riaño E, Dewhurst S, Topham DJ, Martínez-Sobrido L. (2014). Influenza A virus attenuation by codon deoptimization of the NS gene for vaccine development. J. Virol. PMID: 24965472

Baker SF*, Guo H*, Albrecht RA, García-Sastre A, Topham DJ, Martínez-Sobrido L. (2013). Protection against lethal influenza with a viral mimic. J. Virol. PMID: 23720727

Full bibliography available: https://www.ncbi.nlm.nih.gov/myncbi/steven.baker.2/bibliography/public/